A defect of intestinal absorption caused by abnormal sensitivity to gluten in the diet that can first manifest with recurrent miscarriage or unexplained infertility, despite an absence of diarrhea or other disturbances of bowel function. Diagnosis is suggested by serum antigliadin antibodies and serum tissue transglutaminase (or endomysial) antibodies, but requires biopsy of the lining of the small intestine via gastroscopy for confirmation. Responds to a gluten-free diet.

Antibodies to gliadin, a component of dietary gluten, and present in wheat, barley, rice and oats, found in celiac disease, a defect of intestinal absorption caused by abnormal sensitivity to gluten.