Curettage in which the contents of the early pregnant uterus are sucked out using a soft plastic catheter. Used in the treatment of miscarriage, in the treatment of hydatidiform mole, and to induce abortion.

The operation of scraping out the contents of a hollow cavity (such as the endometrial cavity of the uterus) with a curette, for making a diagnosis or for therapeutically removing abnormal tissue. A D and C is abbreviated jargon for dilatation of the cervix and curettage of the uterus). When a curettage is done to empty the uterus of normal or abnormal pregnancy tissue, a special suction apparatus is used and we refer to the operation as a vacuum curettage.

A hydatidiform mole in which there is no embryo or fetus. The size of the uterus is often larger than expected from the date of the last menstrual period, often with a high level of serum hCG; there may be bleeding; and there is a classic abnormal appearance on transvaginal ultrasound. Caused by pregnancy following abnormal fertilisation in which the oocyte is 'empty', that is it loses its pronucleus, and either (1) the male pronucleus from a single fertilising sperm doubles (the karyotype of the mole is then always 46,XX, because 46,YY is immediately lethal) or (2) there are two male pronuclei from two fertilising sperm (in which case the karyotype is either 46,XX or 46,XY). Treatment is by vacuum curettage, but there is a persisting danger of cancer (choriocarcinoma) and specialist medical follow-up is essential.